![]() However, differences in the exact way of measuring this space result in clinically significant different results and, therefore, debate remains about the true value of this measured parameter.Ĭopyright © 2023, StatPearls Publishing LLC. This includes any breathing system or airway plus mouth, trachea and the airways up until the start of the respiratory zone. Indeed, it may serve as a prognostic factor in patients with acute repository distress syndrome (ARDS) who require ventilation. This phenomenon has clinical significance because, both in healthy and impaired lungs, properly calculating and accounting for this non-physiological space is important for the proper respiratory care of ventilated patients. Physiologic dead space is the sum of anatomic dead space and alveolar dead space. This is therefore termed anatomical dead space as it serves no respiratory function. Anatomic dead space is the total volume of the conducting airways from the nose or mouth down to the level of the terminal bronchioles it includes the nose, mouth, nasopharynx, larynx, trachea, bronchus, bronchioles, and terminal bronchioles. ![]() ![]() Anatomic dead space is an important phenomenon in respiratory physiology whereby, owing to the fact that upper airways do not function as locations for gas exchange, and because of the tidal nature of ventilation, there is always a fraction of the inspired air that does not perform a physiologic function of exchanging carbon dioxide for oxygen. ![]()
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